This course will provide evidence-based strategies to address frequently encountered medically unexplained conditions. We will begin with a thorough discussion of the pathophysiological process of central sensitization; this will be followed by lectures focusing on specific medically unexplained conditions and symptoms. Each topic will utilize didactic sessions, case vignettes, clinical pearls, and formal Q/A sessions. This course will also incorporate an optional workshop on Healthy Living based on the Mayo Clinic Healthy Living Program one afternoon of the course. Time: 7:00 am - 1:00 pm